abstract：:Leucine-rich repeats and immunoglobulin-like domains (LRIG) 3 gene is mapped to chromosome 12q13.2, a region that is frequently deleted in a subset of glioblastoma multiforme (GBM). It has been reported that perinuclear LRIG3 staining correlated with low WHO grade of glioma and better survival of the patients. However...

journal_title：Journal of the neurological sciences

authors： Guo D,Yang H,Guo Y,Xiao Q,Mao F,Tan Y,Wan X,Wang B,Lei T

更新日期：2015-03-15 00:00:00

abstract：BACKGROUND:Data on recent stroke trends in the context of rapidly deteriorating risk profile of populations within Africa is very limited. We investigated the admission trend for stroke and related outcomes in a major referral hospital in Cameroon. METHODS:Admission and discharge registries, and patient files for the ...

journal_title：Journal of the neurological sciences

authors： Lekoubou A,Nkoke C,Dzudie A,Kengne AP

更新日期：2015-03-15 00:00:00

abstract：BACKGROUND:Neurofibromatosis 1 (NF1) belongs to the autosomal dominant neurocutaneous disorders' group, which mainly includes NF1 and NF2, tuberous sclerosis, von Hippel-Lindau disease and Cerebral Cavernous Malformations (CCMs). NF1 has a major impact on the nervous system, eye, skin, bone or cardiovascular system. Ce...

journal_title：Journal of the neurological sciences

authors： Rerat K,Parker F,Nasser G,Vidaud D,Riant F,Tournier-Lasserve E,Denier C

更新日期：2015-03-15 00:00:00

abstract：:We assessed the relationship between key trace elements and neurocognitive and motor impairments observed in konzo, a motor neuron disease associated with cassava cyanogenic exposure in nutritionally challenged African children. Serum concentrations of iron, copper, zinc, selenium, and neurotoxic lead, mercury, mangan...

journal_title：Journal of the neurological sciences

authors： Bumoko GM,Sadiki NH,Rwatambuga A,Kayembe KP,Okitundu DL,Mumba Ngoyi D,Muyembe JJ,Banea JP,Boivin MJ,Tshala-Katumbay D

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:Postural instability is often experienced in the late stages of PD and is a marker of disease progression. Little information is available on the role of visual inputs as an adaptive strategy to compensate for postural instability in PD. The purpose of this study was to determine visual dependency for postur...

journal_title：Journal of the neurological sciences

authors： Panyakaew P,Anan C,Bhidayasiri R

更新日期：2015-02-15 00:00:00

abstract：:This study evaluated the effect of low-level laser therapy (LLLT; 15 J/cm(2)) and a latex protein (F1) on a crush injury of the sciatic (ischiadicus) nerve. Seventy-two rats (male, 250 g) were divided into 6 groups: CG, control; EG, exposed nerve; IG, injured nerve without treatment; LG, injured nerve with LLLT; HG, i...

journal_title：Journal of the neurological sciences

authors： Dias FJ,Issa JP,Coutinho-Netto J,Fazan VP,Sousa LG,Iyomasa MM,Papa PC,Watanabe IS

更新日期：2015-02-15 00:00:00

abstract：:We describe detailed clinical, biochemical, neuroimaging and neuropathological features in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), encompassing hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) and pigmentary orthochromatic leukodystrophy (POLD), linked to col...

journal_title：Journal of the neurological sciences

authors： Kim EJ,Shin JH,Lee JH,Kim JH,Na DL,Suh YL,Hwang SJ,Lee JH,Lee YM,Shin MJ,Lee MJ,Kim SJ,Yoon U,Park DY,Jung DS,Ahn JW,Sung S,Huh GY

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND:Olfactory identification impairment in amnestic mild cognitive impairment (aMCI) patients is well documented and considered to be caused by underlying Alzheimer's disease (AD) pathology, contrasting with less clear evidence in non-amnestic MCI (naMCI). The aim was to (a) compare the degree of olfactory ident...

journal_title：Journal of the neurological sciences

authors： Vyhnalek M,Magerova H,Andel R,Nikolai T,Kadlecova A,Laczo J,Hort J

更新日期：2015-02-15 00:00:00

abstract：BACKGROUND AND PURPOSE:Post-conditioning with volatile anesthetics can create ischemic tolerance against cerebral ischemia-reperfusion injury. The present study was designed to determine whether delayed exposure to sevoflurane could induce ischemic tolerance and if this effect was dependent on increasing phosphorylated...

journal_title：Journal of the neurological sciences

authors： Ye Z,Xia P,Cheng ZG,Guo Q

更新日期：2015-01-15 00:00:00

abstract：BACKGROUND:Paraneoplastic neurological syndromes (PNS) are poorly described in patients without onconeural antibodies and in patients with non-small cell lung cancer (NSCLC). We compared the clinical characteristics of PNS in lung cancer patients with and without onconeural antibodies. METHODS:Medical records from pat...

journal_title：Journal of the neurological sciences

authors： Raspotnig M,Vedeler C,Storstein A

更新日期：2015-01-15 00:00:00

abstract：:This study indicates the impact of nicotine and pesticides (organochlorine and organophosphate insecticides used in agriculture) on neuronal α7-nicotinic acetylcholine receptor expression in brainstem regions receiving cholinergic projections in human perinatal life. An in-depth anatomopathological examination of the ...

journal_title：Journal of the neurological sciences

authors： Lavezzi AM,Cappiello A,Pusiol T,Corna MF,Termopoli V,Matturri L

更新日期：2015-01-15 00:00:00

abstract：:Baló's concentric sclerosis (BCS) and tumefactive demyelination (TD) are considered atypical forms of multiple sclerosis (MS). Baló lesions are characterized by concentric rings corresponding to alternating bands of demyelination and relatively preserved myelin (Hu and Lucchinetti, 2009). Tumefactive lesions are pseud...

journal_title：Journal of the neurological sciences

authors： Hardy TA,Beadnall HN,Sutton IJ,Mohamed A,Jonker BP,Buckland ME,Barnett MH

更新日期：2015-01-15 00:00:00

abstract：OBJECTIVE:To describe the alterations of the cortical microcirculation of the brain (blood flow and vessel density) in TBI patients who and compare them with a control group. METHODS:Prospective and observational study in a third-level university hospital. Cortical microcirculation in the brain was directly observed u...

journal_title：Journal of the neurological sciences

authors： Pérez-Bárcena J,Romay E,Llompart-Pou JA,Ibáñez J,Brell M,Llinás P,González E,Merenda A,Ince C,Bullock R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:We recently reported that left versus right hemisphere cerebral infarctions patients more frequently have worse outcomes. However our clinical experience led us to suspect that the incidence of malignant middle cerebral artery infarctions (MMCA) was higher in the right compared to the left hemispheric stroke...

journal_title：Journal of the neurological sciences

authors： Rastogi V,Lamb DG,Williamson JB,Stead TS,Penumudi R,Bidari S,Ganti L,Heilman KM,Hedna VS

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to determine the effectiveness of hypoglossal-facial nerve "side"-to-end (HemiHN-FN) and accessory-facial nerve end-to-end (AN-FN) neurorrhaphy using a predegenerated nerve graft (PNG) for reanimating facial paralysis in a rat FN injury model. A total of 25 rats with complete unilateral facia...

journal_title：Journal of the neurological sciences

authors： Li D,Wan H,Feng J,Wang S,Su D,Hao S,Schumacher M,Liu S

更新日期：2014-12-15 00:00:00

abstract：:Bacillus Calmette-Guérin (BCG) and Mycobacterium avium subspecies paratuberculosis (MAP) have been associated with multiple sclerosis (MS). Clinical data indicates that BCG vaccination exerts anti-inflammatory effects in MS; conversely, MAP is thought to be one of the possible infectious factors responsible of MS thro...

journal_title：Journal of the neurological sciences

authors： Cossu D,Mameli G,Masala S,Cocco E,Frau J,Marrosu MG,Sechi LA

更新日期：2014-12-15 00:00:00

abstract：:The notion that there is an association between essential tremor (ET) and higher ethanol consumption has crept into the literature; however, the data are limited and conflicted. A total of 354 ET cases and 370 matched controls were enrolled in a clinical-epidemiological study. Average current daily ethanol consumption...

journal_title：Journal of the neurological sciences

authors： Louis ED,Michalec M

更新日期：2014-12-15 00:00:00

abstract：:Tartarian Buckwheat is an effective hypoglycemic medicinal herb. Its main active ingredients are flavonoids. We report here 5 cases of new onset polyneuropathy with dyskinesia prospectively induced by tartarian buckwheat products. Clinical and electrophysiological evidence along with laboratory tests were reviewed and...

journal_title：Journal of the neurological sciences

authors： Yang F,Yu SY,Wang Y,Wang RF,Jing F

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Repeated administration of Paced Auditory Serial Addition Test (PASAT) results in a considerable learning effect in short- or long-term follow-up studies. However, the relationship between PASAT learning and changes in magnetic resonance imaging (MRI) parameters is yet to be investigated. OBJECTIVES:The aim...

journal_title：Journal of the neurological sciences

authors： Uher T,Benedict RH,Horakova D,Bergsland N,Dusankova JB,Tyblova M,Ramasamy DP,Seidl Z,Vaneckova M,Krasensky J,Havrdova E,Zivadinov R

更新日期：2014-12-15 00:00:00

abstract：:Increasing evidence shows that exposure to an enriched environment (EE) after cerebral ischemia/reperfusion injury has neuroprotective benefits in animal models, including enhancing functional recovery after ischemic stroke. However, the mechanism underlying this effect remains unclear. To clarify this critical issue,...

journal_title：Journal of the neurological sciences

authors： Yu K,Wu Y,Zhang Q,Xie H,Liu G,Guo Z,Li F,Jia J,Kuang S,Hu R

更新日期：2014-12-15 00:00:00

abstract：:Parkinson's disease (PD) is a common disorder of the central nervous system in the elderly. The pathogenesis of PD is a complex process, with genetics as an important contributing factor. This factor may stem from mitochondrial gene variations and mutations as well as from nuclear gene variations and mutations. More r...

journal_title：Journal of the neurological sciences

authors： Andalib S,Vafaee MS,Gjedde A

更新日期：2014-11-15 00:00:00

abstract：:Perception of verticality is essential for postural control. On the other hand, postural instability is one of the cardinal features in Parkinson's disease (PD). Thus, the objective of this study was to evaluate the vertical perception using the subjective visual vertical test in PD patients with different degrees of ...

journal_title：Journal of the neurological sciences

authors： Pereira CB,Kanashiro AK,Maia FM,Barbosa ER

更新日期：2014-11-15 00:00:00

abstract：:Adult-onset, chronic progressive spastic paraparesis may be due to a large number of causes and poses a diagnostic challenge. There are no recent evidence-based guidelines or comprehensive reviews to help guide diagnostic work-up. We survey the literature on chronic progressive spastic paraparesis, with special emphas...

journal_title：Journal of the neurological sciences

authors： Zhovtis Ryerson L,Herbert J,Howard J,Kister I

更新日期：2014-11-15 00:00:00

abstract：:The role of excitotoxicity on the neuropathology of glutaric acidemia type I (GA I) is still under debate. Therefore, in the present work, we evaluated glutamate uptake by brain slices and glutamate binding to synaptic membranes, as well as glutamine synthetase activity in cerebral cortex and striatum from glutaryl-Co...

journal_title：Journal of the neurological sciences

authors： Busanello EN,Fernandes CG,Martell RV,Lobato VG,Goodman S,Woontner M,de Souza DO,Wajner M

更新日期：2014-11-15 00:00:00

abstract：:To evaluate the association between the tumor necrosis factor beta (TNF-β) NcoI polymorphism and inflammatory and metabolic markers in patients with multiple sclerosis (MS) patients and the association of these markers with disease disability, a 782 base-pair fragment of the TNF-β gene was amplified from genomic DNA a...

journal_title：Journal of the neurological sciences

authors： Kallaur AP,Oliveira SR,Simão AN,de Almeida ER,Morimoto HK,Alfieri DF,Pereira WL,Borelli SD,Kaimen-Maciel DR,Maes M,Reiche EM

更新日期：2014-11-15 00:00:00

abstract：OBJECTIVE:We carried out a meta-analysis focusing on the relationships between rs1137070 C>T and rs1799836 A>G polymorphisms in the MAO gene as a modifier of Parkinson disease (PD) susceptibility. METHOD:A literature search of the Cochrane Library Database, Web of Science, PubMed, CINAHL, EMBASE, and the Chinese Biome...

journal_title：Journal of the neurological sciences

authors： Sun YX,Wang XH,Xu AH,Zhao JH

更新日期：2014-10-15 00:00:00

abstract：:Tacrolimus, also known as FK506, is an immunosuppressive agent widely used for the prevention of acute allograft rejection in organ transplantation and for the treatment of immunological diseases. This study reports two male patients who underwent solid organ transplantation (liver and kidney). After transplant, the p...

journal_title：Journal of the neurological sciences

authors： Vattemi G,Marini M,Di Chio M,Colpani M,Guglielmi V,Tomelleri G

更新日期：2014-10-15 00:00:00

abstract：PURPOSE:T cells are important in the immunopathology of immune-mediated peripheral neuropathies (PNP) and activated vitamin D regulates the immune response through increasing the amount of regulatory T cells. An association between vitamin D deficiency and polyneuropathy has been stipulated; hence we assessed whether p...

journal_title：Journal of the neurological sciences

authors： Elf K,Askmark H,Nygren I,Punga AR

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:The association between the angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism and risk of ischemic stroke (IS) remains controversial and ambiguous. To clarify this association, a large meta-analysis was performed. METHODS:Electronic databases in both English and Chinese were used to id...

journal_title：Journal of the neurological sciences

authors： Zhao J,Qin X,Li S,Zeng Z

更新日期：2014-10-15 00:00:00

abstract：:Traumatic brain injury (TBI) is a considerable cause of mild cognitive impairment and dementia. Intranasal administration of nerve growth factor (NGF) has previously been found to improve cognitive function after TBI, but the mechanism remains unclear. This study aimed to investigate the effects of intranasal NGF on t...

journal_title：Journal of the neurological sciences

authors： Lv Q,Lan W,Sun W,Ye R,Fan X,Ma M,Yin Q,Jiang Y,Xu G,Dai J,Guo R,Liu X

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:The mechanisms for improved cognitive function post-bariatric surgery are not well understood. Markers of kidney and liver function (i.e., cystatin C and alkaline phosphatase (ALP)) are elevated in obese individuals and associated with poor neurocognitive outcomes in other samples. Bariatric surgery can impr...

journal_title：Journal of the neurological sciences

authors： Alosco ML,Spitznagel MB,Strain G,Devlin M,Cohen R,Crosby RD,Mitchell JE,Gunstad J

更新日期：2014-10-15 00:00:00

abstract：BACKGROUND:The likelihood of severe disability and death increases with each recurrent stroke. Repeated intravenous (IV) thrombolysis remains one of the therapeutic options when secondary prevention fails; however, its effects after recurrent stroke are largely unknown. The aim of the present review was to assess the r...

journal_title：Journal of the neurological sciences

authors： Cappellari M,Moretto G,Bovi P

更新日期：2014-10-15 00:00:00

abstract：:Isoflavone formononetin is a typical phytoestrogen isolated from Chinese medical herb red clover. It has been reported that estrogens have neuroprotective properties, and dietary intake of phytoestrogens could reduce stroke injury in cerebral ischemia/reperfusion (I/R) animal models. In the present research, we sought...

journal_title：Journal of the neurological sciences

authors： Liang K,Ye Y,Wang Y,Zhang J,Li C

更新日期：2014-09-15 00:00:00

abstract：:Protein stabilization and oligonucleotide therapies are being tested in transthyretin amyloid polyneuropathy (TTR FAP) trials. From retrospective analysis of 97 untreated TTR FAP patients, we test the adequacy of Neuropathy Impairment Score+7 tests (NIS+7) and modifications to comprehensively score impairments for use...

journal_title：Journal of the neurological sciences

authors： Suanprasert N,Berk JL,Benson MD,Dyck PJ,Klein CJ,Gollob JA,Bettencourt BR,Karsten V,Dyck PJ

更新日期：2014-09-15 00:00:00

abstract：BACKGROUND:Patients with complaints of carpal tunnel syndrome (CTS) with signs and symptoms not exclusively confined to the median nerve territory, but otherwise fulfilling the clinical criteria may erroneously be withheld from therapy. METHODS:One hundred and twenty one patients who fulfilled the clinical criteria fo...

journal_title：Journal of the neurological sciences

authors： Claes F,Kasius KM,Meulstee J,Grotenhuis JA,Verhagen WI

更新日期：2014-09-15 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Autonomic disturbances and sleep problems are common non-motor symptoms in patients with Parkinson's disease (PD). Orthostatic hypotension, supine hypertension (SH), and nocturnal hypertension (NH) are inter-related in patients with PD. These abnormalities might be associated with restless legs...

journal_title：Journal of the neurological sciences

authors： Oh YS,Kim JS,Park IS,Song IU,Son YM,Park JW,Yang DW,Kim HT,Lee KS

更新日期：2014-09-15 00:00:00

abstract：:A 52-year-old Japanese woman complaining of horizontal double vision for 10 days was admitted to our hospital. Neurological examination revealed left abducent nerve palsy and muscle swelling in her thighs. Brain MRI showed obstruction in the spinal fluid space of the left Dorello's canal, which transmits a portion of ...

journal_title：Journal of the neurological sciences

authors： Shioya A,Takuma H,Shiigai M,Ishii A,Tamaoka A

更新日期：2014-08-15 00:00:00

abstract：:Psychiatric disorders seem to be more frequent in patients with epilepsy (PWE) than the general population. Although researchers have documented a strong association between epilepsy and psychiatric comorbidities, the nature of this relationship is poorly understood. According to this, psychiatric diseases are often u...

journal_title：Journal of the neurological sciences

authors： Verrotti A,Carrozzino D,Milioni M,Minna M,Fulcheri M

更新日期：2014-08-15 00:00:00

abstract：:Charcot-Marie-Tooth disease type 1 (CMT1) is a common disorder of the peripheral nervous system. The underlying genetic cause is highly heterogeneous, and mutations in SIMPLE (small integral membrane protein of lysosome/late endosome) represent a rare cause of CMT type 1, named CMT1C. Herein, we report the clinical, e...

journal_title：Journal of the neurological sciences

authors： Ciotti P,Luigetti M,Geroldi A,Capponi S,Pezzini I,Gulli R,Pazzaglia C,Padua L,Massa R,Mandich P,Bellone E

更新日期：2014-08-15 00:00:00

abstract：:Antibodies against LGI1 (leucin-rich glioma-inactivated 1 protein) are associated with limbic encephalitis (LE), which is characterized by a favorable outcome following immunotherapy. Here, we present two cases, where antibodies against LGI1 were detected in the sera 36 and 53 months after acute LE, respectively, and ...

journal_title：Journal of the neurological sciences

authors： Szots M,Marton A,Kover F,Kiss T,Berki T,Nagy F,Illes Z

更新日期：2014-08-15 00:00:00